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Data availability The data generated or analysed during this study are included in this published article and its supplementary information files

When combined, these effects make it especially important to monitor blood pressure and cardiovascular symptoms

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This may be because vitamin B12 plays a crucial role in the creation of serotonin - a neurotransmitter responsible for regulating our moods

Patients should be asked if their pain is worsened with bladder filling (painful bladder filling) and/or their strong urge to urinate was due to pain, pressure, or discomfort (painful urgency), since these are characteristic symptoms of IC/BPS