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It causes the separation of DNA strands and by inserting itself between DNA base pairs, it disrupts DNA and RNA synthesis, thereby stalling the movement of topoisomerase II, leading to DNA damage and initiation of apoptosis (Johnson-Arbor et al., 2017)

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Initial results from fat-dissolving injections can be seen within a few days, with full results becoming more apparent over several weeks as the body processes and eliminates the broken-down fat cells

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However, studies in animals found that the effects of Tresiba in pregnancy were similar to those seen with normal human insulin