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95.6% CI, 0.691.12 and exploratory HR, 0.84

Glossary of Key Terms GLP-1 receptor agonists: A class of medications (including semaglutide and tirzepatide) that mimic the glucagon-like peptide-1 hormone

By activating both GIP and GLP-1 receptors, Zepbound enhances insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and reduces appetite through central nervous system pathways