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Starting doses differ significantly: IR begins at 5mg twice daily with a 40mg daily maximum, while XR starts at 10mg once daily with a 60mg daily ceiling

They have read that peptides can replace hormone replacement therapy, or they assume any peptide will fix any hormone problem

What you'll notice: Probably nothing visible yet

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Causes include: Neurobiological factors (hypersensitivity of the ejaculatory reflex) Hormonal imbalances Inflammation or infection of the prostate or urethra Psychological factors such as anxiety, guilt, or depression Relationship issues Early sexual experiences that conditioned rapid ejaculation Many men with PE also develop secondary erectile dysfunction due to performance anxiety, creating a cycle that can be difficult to break without proper treatment