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[DOI] [PubMed] [Google Scholar] 19.Husain M, et al
For instance, a large network meta-analysis showed that SGLT-2 inhibitors reduced hospitalization for HF and renal composite outcome more than GLP-1RA [15], and that in patients with cardiovascular disease, SGLT-2 inhibitors show significant reduction in both heart failure (HF) hospitalizations and mortality for patients with HF and reduced ejection fraction [16]
Both melphalan and chlorambucil are larger molecules than most of the compounds studied in this work, and they possess aromatic rings in their chains, which increases their hydrophobicity
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