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Unlike GHK-Cu, which occurs naturally in the human body and has broad skin research behind it, AHK-Cu was designed with hair biology in mind - particularly its potential to interact with the Wnt/-catenin signalling pathway involved in hair follicle cycling

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Future efforts should prioritize incorporating multi-channel compound exposure and high-content imaging within microfluidic platforms to identify synergistic dosing strategies of plant-derived anti-inflammatory compounds, thereby addressing the current lack of mechanistic and dosimetric rationale for clinical combination therapies

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40 KatagiriS.ShibaT.ToharaH.YamaguchiK.HaraK.NakagawaK.et al (2019)