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Schwechheimer et al., 2016)

Rapid weight loss and reduced food intake can increase the risk of muscle loss if protein intake and strength training are not prioritized

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Ferroptosis can be triggered by GSH depletion, which can be achieved by inhibiting GSH biosynthesis (e.g., buthionine sulfoximine (BSO) inhibits -glutamylcysteine synthetas (-GCS)) or blocking the uptake of cysteine from the extracellular environment (e.g., erastin inhibits the Xc system) [126, 127]