While injection site reactions are generally self-limiting and not indicative of serious complications, patients should be educated about normal versus concerning symptoms
NICE guidance (NG28) supports the use of GLP-1 receptor agonists in type 2 diabetes when metformin is insufficient, specifically for patients with a BMI 35 kg/m (or 30 kg/m with weight-related comorbidities), or for whom insulin would have significant occupational implications, or for whom weight loss would benefit obesity-related comorbidities
For women: BMR = (10 x weight in kg) + (6.25 x height in cm) - (5 x age) - 161 For men: BMR = (10 x weight in kg) + (6.25 x height in cm) - (5 x age) + 5 For example, a 40-year-old woman who weighs 200 pounds (91 kg) and stands 5 feet 6 inches (168 cm) would calculate: (10 x 91) + (6.25 x 168) - (5 x 40) - 161 = 910 + 1,050 - 200 - 161 = 1,599 calories
Semaglutide has a seven-day half-life, so two-week intervals would leave you without therapeutic drug levels for seven days of each cycle
My hair started thinning about three years ago