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Preclinical studies report that IL-6 may promote GLP-1 release from intestinal L-cells

In Western populations, the annual incidence of VTE is estimated at approximately 12 cases per 1,000 person-years ( Prior studies have shown that obesity confers more than a twofold higher risk of a first episode of VTE compared with normal weight ( However, evidence remains limited regarding whether tirzepatide use is associated with a reduced incidence of VTE compared with GLP-1 RAs among patients with obesity

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Medical weight loss is more than just diet and exercise advice