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No clinically validated or universally accepted KLOW ratio was identified

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Not resting enough Rest and recovery is one of the three pillars of muscle building but probably the most easily neglected

We then intercrossed the F1 offspring to generate the following F2 offspring: Nestin-Cre ER :: Igf1r fl/fl (homozygous IGF1R inducible knockout mice, hereafter referred to as MSC- Igf1r / ), Nestin-Cre ER :: Igf1r fl/+ (heterozygous IGF1R inducible knockout mice), and mice without either the Nestin-Cre ER or a floxed Igf1r allele (hereafter referred to as wild type) (Figure 2)

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