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The SUSTAIN-7 trial compared the GLP-1 RAs Ozempic and Trulicity against each other in individuals that had type 2 diabetes over a 40-week period
However, this benefit comes with a trade-off: eating much less can sometimes mean taking in fewer essential nutrients
Mol Aspects Med, 2009
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Excess intracellular and intravascular FFAs (as is the situation in diabetic and obese individuals) result in the accumulation of fatty acid metabolic byproducts, such as ceramides, fatty acyl-CoAs, and diacylglycerol
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