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Psychosom Med 2004;66:276-82

However, the researchers did not observe the protective effect of CDDO-Im on the liver in Nrf2 knockout mice (Reisman et al., 2009)

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Inhibition of cell migration and invasion The epithelial-to-mesenchymal transition (EMT) describes a process of epithelial cell transformation whereby cells lose their polarity and adhesion properties while gaining migratory and invasive properties through the expression of mesenchymal genes