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10.1128/spectrum.00849-23 377 RanisavljevM.StajerV.TodorovicN.OstojicJ.CvejicJ

Oxidative stress or other conditions that deplete glutathione in the epithelium of the oral, nasal, and upper airway may, therefore, enhance susceptibility to influenza infection

In PTSD mice models, trauma exposure increased tyrosine hydroxylase expression (the rate-limiting enzyme in catecholamine biosynthesis), elevating stress hormones epinephrine and norepinephrine in serum and colon, which upregulated claudin-2 expression, confirming gut barrier dysfunction (Yadav et al., 2023)

Long-term benefits are studied for healthspan extension, disease prevention, and biological age optimization