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This underdiagnosis can lead, besides death in 20% when it is not appropriately treated, to Korsakoffs syndrome, a severe dysfunction often following untreated Wernickes encephalopathy, that does not remit even with thiamine treatment and is associated with chronic alcohol abuse and chronic thiamine deficiency (40, 42)

Additionally, genetic variation in immune response pathways impacts an individual's innate antifungal defenses and susceptibility to Candida colonization

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Though Adele emphasizes that her transformation was about mental well-being , not appearance, her story highlights the importance of holistic health approaches , including weight management strategies that are customized for long-term success