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Both versions help regulate blood sugar and appetite in a few key ways: They prompt your pancreas to release insulin, slow digestion and signal to your brain that you're full

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The drug led to an average weight loss of 70.3 pounds over 80 weeks in patients with obesity, with 45% of patients on 12 mg of the once-weekly injectable retatrutide losing up to 30% of their body weight, the drugmaker, Eli Lilly and Company, said in a news release

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Drinking plenty of fluids may reduce your chance of dehydration

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These trials included a total of 630 participants and used exenatide or dulaglutide as GLP-1 receptor agonists

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