In the second test, they grew hamster cells in the laboratory and treated them with AOD9604, then examined the chromosomes under a microscope to see if any were broken or rearranged
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The results suggest that HTYs in vivo cardioprotective effects may be mediated in part by its circulating metabolites rather than the parent molecule, therefore, the demonstrated signaling modulation of free HTY effects should be interpreted as indirect modulation through oxidative stress-related markers rather than direct plaque-regressive action
Ting Chen National Institute of Biological Sciences, Beijing, China Contribution TC, Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting or revising the article, Contributed unpublished essential data or reagents For correspondence [email protected] Competing interests The authors declare that no competing interests exist
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