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Before starting weight loss injections , arrange a consultation with your GP if you: Have known gallstones or previous gallbladder problems Have a family history of gallstone disease Have experienced unexplained abdominal pain Are considering rapid weight loss for any reason Have multiple risk factors for gallstones (female sex, age over 40, obesity, rapid previous weight loss) Your doctor will take a comprehensive medical history, perform an examination, and may arrange investigations such as liver function tests or an abdominal ultrasound (the first-line imaging test according to NICE CG188) to assess your gallbladder before recommending treatment options