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2.2 Absorption and metabolism Once synthesized in the colon, UA can be absorbed through intestinal epithelial cells due to its lipophilic nature, subsequently entering the circulatory system via enterohepatic circulation

Despite these interventions, the mortality rate remains considerably high (Allinson et al., 2023

The possible causes include: Sunspots Sunspots are dark spots that develop on parts of the body that get the most sun exposure, such as the face and hands

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