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Furthermore, we recently reported that pharmacological activation of beta-cell GLP-1R signaling through the administration of a GLP-1R agonist can mimic the effect of VSG to enhance alpha-cell GLP-1 production in HFD-fed mice (13)

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This approach aligns with reduced appetite from semaglutide and prevents the discomfort of overfull feelings while maintaining total daily protein intake of 110200 grams