In fulfilling this protective role, reduced glutathione is converted into oxidized glutathione, at which point it becomes inactive
Therefore, the problem that the agents successful in pre-clinical experimental autoimmune encephalitis trials, were either less effective in patients, worsened disease or caused unexpected, severe adverse events (60), may be at least partly solved with the more suited cuprizone model that reflects a toxic experimental model (12)
Louis, MO), MDA-T32 and MDA-T68 (ATCC, Manassas, VA), and control human thyroid fibroblasts [(HThF)
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