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The evidence indicates that intensive glucose control significantly prevents DPN in T1D but has limited effectiveness in T2D, reasons for this could be that T1D DPN is characterized by more severe structural degenerative changes, progressive axonal atrophy, and paranodal degenerative changes or maybe the difference could be caused owing to different susceptibility of nerve fibers to hyperglycemic damage between the two diabetes types

As research progresses, harms more subtle than acute poisoning are seen at lower and lower body burdens of heavy metals

The sensitivity for these assays is 0.12 ng/mL for T3 and 0.1 g/dL for T4, with high specificity for their respective hormones

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U., Farghaly, A