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In a study conducted on a murine model of MS utilizing experimental autoimmune encephalomyelitis (EAE), the administration of bevacizumab demonstrated promising outcomes

Microdosing is different from the standard titration schedule

1,2 These drugs act on both the central nervous system and the gastrointestinal tract, promoting satiety and reducing food intake, as demonstrated by brain imaging studies using GLP-1-specific tracers

Although a standard random-effects model was employed to account for between-study variability, alternative methodological approaches could have further enhanced the robustness of this analysis

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