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Effects of neuropeptide Y on sucrose and ethanol intake and on anxiety-like behavior in high alcohol drinking (HAD) and low alcohol drinking (LAD) rats

A 2023 retrospective cohort study found semaglutide significantly reduced binge eating episodes in patients with BED the first study of its kind A 2020 pilot study of dulaglutide found it reduced binge episodes in patients with type 2 diabetes and BED A 2026 meta-analysis found liraglutide reduced binge frequency by approximately 1.28 fewer episodes per week compared to placebo A rapid review of 25 studies encompassing over 8,700 adult patients found that binge eating episodes and prevalence reduced following liraglutide and semaglutide An observational study of 69 people with obesity found emotional eating dropped from 72.5% to 11.5% after three months of semaglutide The Critical Caveats Despite a promising early signal, these findings should be held carefully

Wegovy, the FDA-approved semaglutide for weight management, carries a list price exceeding $1,300 per month without insurance

In the work from Thomas et al, they observed a significant but relatively minor increase in resting mean arterial pressure (3 mmHg) and a reduction in resting MCAv (3 cm/s) after 12 weeks of RT

The two compounds are chemically unrelated