Graphics Schematic diagrams (Fig EV2) and the graphical abstract were created using BioRender.com
VIDA 5.0.3: OpenEye Scientific Software, Santa Fe, NM.)
Troy Vitamin B12 Sheep and Cattle 500mL Troy Vitamin B12 Sheep and Cattle in an injectable preparation for the treatment of vitamin B12 deficiency in lambs, calves, sheep and cattle
Its main mechanism of action is based on increasing the expression of BDNF (Brain-Derived Neurotrophic Factor) and its TrkB receptors in the hippocampus and prefrontal cortex, promoting synaptic plasticity, long-term potentiation (LTP), and memory consolidation (Dolotov et al., Neuroscience 2006)
Research is underway to examine how nutritional support targeted at one-carbon metabolism may be helpful for safe excretion of arsenic metabolites from the human body: Folate, betaine and choline sufficiency may have a positive influence where timely methylation and safer excretion of arsenic metabolites are key (Bozack et al, 2020