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Orphan Drug Designation : PWS is recognized as an orphan disease due to its rarity, a classification that often comes with incentives for pharmaceutical companies, such as market exclusivity, tax credits for clinical research, and waiver of marketing application fees, to develop treatments

However, governing bodies are still investigating the long-term effects of GLP-1 drugs

Even then, the rules are a patchwork

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For a common working concentration of 2.5 mg/mL, add 2 mL of solvent directly to the lyophilized vial and allow it to dissolve gently without vortexing, as aggressive agitation can cause peptide aggregation and loss of bioactivity