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Researchers at the University of Utah have identified a new enzyme, called PapB, capable of tying off therapeutic peptides into tight rings, a process known as macrocyclisation

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We currently understand its primary actions to be: GLP-1 (Glucagon-Like Peptide-1) Receptor Agonism: This action is known to enhance insulin secretion in a glucose-dependent manner, slow gastric emptying, and significantly suppress appetite by acting on the central nervous system

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