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They must ensure quality in new manufacturing sites (inspections of multi-billion-dollar plants are scheduled), authorizing tech transfers, and approving new dosage forms

Oxidative stress is crucial in atherogenesis (144151), suggesting that a specific antioxidant/prooxidant imbalance, characterized by a weak GSH-related enzymatic antioxidant shield present in human atherosclerotic lesions, may be involved in atherogenic processes in humans (152)

Int J Immunopharmacol, 13: 621-629

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Senescent cells accumulate with aging and after acute stresses like chemotherapy, secreting inflammatory mediators collectively termed the senescence-associated secretory phenotype (SASP)