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The change over time in HbA1c and body weight were estimated using the mixed model for repeated measures

30 mg/dL or 1.6 mmol/L above their current trigger

Monitor for severe abdominal pain, persistent vomiting, changes in stool frequency or consistency that differ from your baseline colitis pattern, signs of dehydration, and unexplained weight loss beyond your intended loss

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Interestingly, some trial participants reported improved sleep quality on retatrutide, possibly related to weight loss reducing sleep apnea symptoms