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Research indicates it works well during fasting and preserves lean muscle during calorie restriction

Specifically, the hypothalamus controls homeostatic feeding, communicates with the mesolimbic system to modulate hedonic feeding, and interacts with peripheral organs to regulate endocrine pathways involved in hunger and satiety 28,29

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[DOI] [PMC free article] [PubMed] [Google Scholar] 35.Lihn AS, Bruun JM, He G, Pedersen SB, Jensen PF, Richelsen B