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In one study 5 , After NAC treatment, men with infertility experienced improved sperm counts and motility, as well as reduced abnormal morphology, DNA fragmentation, and protamine deficiency

While many POTS patients are instructed to consume high amounts of sodium, failing to balance this with adequate magnesium can lead to neuromuscular excitability and worsening symptoms

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However, the study was small, lacked a placebo control and evaluated biomarkers rather than long-term clinical outcomes

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