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5A) and the CC 50 based on total cell numbers (Fig

Its a glucagon-like peptide-1 (GLP-1) receptor agonist that has shown some pretty impressive results in clinical trials

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Eli Lilly submitted the orforglipron NDA to the FDA in Q1 2026 following ATTAIN Phase 3 trial data showing 14.7% body weight reduction at 45mg positioning the worlds first oral small molecule GLP-1 receptor agonist for obesity for anticipated FDA approval in late 2026 or 2027