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10.1016/j.jaac.2010.05.017 327

The N-terminal threonine residue of small subunit responsible for autoprocessing has also been reported as the relevant nucleophile in enzyme catalysis (Inoue et al., 2000)

The interaction mode of neuromedin C represent alternative activation strategies to the non-peptidic control agonists used in this study (TT-OAD2, danuglipron, LY3502970, and CHU-128), being characterized by a more compact and TM7-localized interaction networks

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