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The production of large amounts of NO by activation of iNOS expression in macrophages represents the major cytotoxic activity of these cells

doi: 10.3389/fped.2025.1514722 Received 21 October 2024 Accepted 03 January 2025 Published 27 January 2025 Volume 13 - 2025 Edited by Sachith Mettananda, University of Kelaniya, Sri Lanka Reviewed by Nishant Chakravorty, Indian Institute of Technology Kharagpur, India J.W

Some studies indicate that astaxanthin can activate a pathway in the body called Nrf2

These cysteine residues can be overmodified by excess reducing agents like glutathione (GSH) and NADPH, resulting in abnormal protein activity and compromised signal transmission

While niacinamide maintains the moisture barrier and gradually lessens discolouration, vitamin C helps revitalise dull, tired-looking skin