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Kates, J

High concentration of H 2 O 2 can produce reactive oxygen species, which potentially causes DNA impairment and propagate cancer [1-3]

Developing robust analytical methods and ensuring high purity standards will be essential for future clinical development

Taken together, these findings underscore the importance of the dynamic balance between glycolysis (EMP, generating critical metabolites such as ATP) and the HMP pathway (generating the critical reducing equivalent, NADPH necessary for full glycolytic flux) in the RBC

Current newborn screening includes assessment of 34 core conditions which allows for early treatment intervention should a positive finding result