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Most people experience side effects About 80 percent of adults taking tirzepatide or semiglutide, the active ingredients in the most commonly prescribed GLP-1s, experienced at least one side effect, according to a 2024 review study published in the journal Obesity Pillars

Importantly, this research also highlights the criticality of investigating glutamine metabolism within the context of tumor immunity

Several FDA-approved medications for weight management operate through entirely different pathways, and for some people, these options work better than GLP-1 agonists

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Both companies are also expanding beyond obesity into adjacent conditions, which could reinforce the long-term investment case