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In patients with moderate hepatic impairment (Child-Pugh score 7 to 9), the maximum recommended dosage is phentermine and topiramate extended-release capsules 7.5 mg/46 mg orally once daily

Oral Administration Convenience No injectionssimple daily capsule use

Subsequent phosphorylation of IRS triggers the AKT signaling pathway, a critical downstream event linked to enhanced neuroprotection, improved synaptic plasticity, and better cognitive function in Alzheimer's disease patients (163)

The impact is going to be huge now that its more affordable. However, both stressed that this is not a quick solution