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Weight loss-induced increase in fasting ghrelin concentration is a predictor of weight regain: evidence from the diabetes remission clinical trial (DiRECT)

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Patients should be aware of serious adverse effects requiring medical attention, including: severe abdominal pain with or without vomiting (pancreatitis)

SREBP2 is a major participant in the cholesterol biosynthesis pathway, functioning as a key transcriptional regulator of cholesterol synthesis (21, 22)