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Semaglutide is administered as a subcutaneous injection that deposits the compound into fatty tissue beneath your skin, bypassing your digestive system entirely

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This agent is selectively cytotoxic for abnormal melanocytes due to the reversible inhibition of tyrosinase and the inhibition of mitochondrial enzymes.136 It is applied twice a day for 2 to 12 weeks, depending on response.1 Treatment results have been highly variable,137139 and there is insufficient evidence to recommend its use over other modalities in clinical practice

Mehta LS, Velarde GP, Lewey J, Sharma G, Bond RM, Navas-Acien A, et al