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The Glucagon-Like peptide 1 receptor agonist exenatide inhibits small intestinal motility, flow, transit, and absorption of glucose in healthy subjects and patients with type 2 diabetes: A randomized controlled trial
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In the STEP trials, semaglutide produced average weight loss of roughly 15 to 17% of body weight, while tirzepatide in the SURMOUNT trials reached approximately 20 to 22%
In contrast, HbA1c demonstrates low within-person variability, providing a stable measure of average glucose over time
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