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QODG at 150 M had the greatest effect on cell viability and was used for subsequent experiments

According to the 2024 American Diabetes Association Standards of Care, GLP-1 receptor agonists have become first line pharmacotherapy for most patients with type 2 diabetes mellitus (T2DM), including those with concomitant atherosclerotic cardiovascular disease (ASCVD), indicators of high ASCVD risk, or chronic kidney disease

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11 The 24-hour pattern of BP changes with tirzepatide was further characterised in a subset (n=600) of SURMOUNT-1 participants, using ambulatory blood pressure monitoring (ABPM)

That is what CMS and manufacturers settled on, not what you pay