glp-1 optimization consultation maryland Optimizing nutrition, diet, and lifestyle communication in medication therapy for weight management: A qualitative research study with registered dietitians Compounded GLP-1 | Joi +

Johnson, V

My Approach When Prescribing Here's my general framework not a rigid protocol, but a starting point for the conversation: I Tend to Start with Semaglutide When The patient has established cardiovascular disease (because of the SELECT trial data) Insurance covers semaglutide but not tirzepatide The patient has MASH/fatty liver disease Cost is the primary concern and semaglutide is more accessible I Tend to Start with Tirzepatide When Maximum weight loss is the primary goal The patient has type 2 diabetes (tirzepatide shows greater A1C reduction roughly 2.02.5% vs 1.02.0% for semaglutide) The patient has tried semaglutide with insufficient results Insurance covers both options equally Regardless of which medication we choose, I always emphasize that GLP-1 therapy is most effective when combined with nutritional counseling, physical activity, and behavioral support

doi: 10.1111/dom.12824 10 ZaazoueeMSHamdallahAHelmySKHasaboEASayedAKGbreelMIet al

This is a practical Houston concern that many clinics dont mention

10.1038/s41586-018-0849-9 Nature 18 HolstJ