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Concurrently, PPIs, frequently prescribed to diabetic patients for gastroesophageal reflux disease management, impair protein-bound vitamin B12 release from dietary sources in the non-acidic gastric environment, with prolonged use ( 2 years) conferring a 65% increased risk of deficiency [159]

10I, Additional file 11: Fig

You can read the full article at Efficacy and safety of tirzepatide monotherapy compared with dulaglutide in Japanese patients with type 2 diabetes (SURPASS J-mono): a double-blind, multicentre, randomised, phase 3 trial In a phase 3 trial conducted in Japan, the efficacy and safety of tirzepatide, a new medication for type 2 diabetes, were compared to dulaglutide

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