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GLP-1 receptors are distributed throughout multiple organ systems, including the pancreas, gastrointestinal tract, cardiovascular system, and importantly, the central nervous system

In the nervous system, the presence of GLP-1 receptors in the brainstem and their vagal connection suggests that the effects on taste may be secondary to central modulation rather than direct peripheral action (157, 170) but also, in vitro and clinical studies may suggest changes in perception of sweet, bitter and salt flavors as a reflection of GLP-1 on TBC (67, 178)

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(2016) Dual function fibroblast growth factor 21 proteins US9458214B2-Figs

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