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In vitro permeation and biological activity of punicalagin and zinc (II) across skin and mucous membranes prone to Herpes simplex virus infection

Since HCV isolates apart from JFH1 require massive adaptation to allow infectious particle production 22 , including the GLT1 isolate 21 , we employed chimeric genomes encoding the JFH1 replicase fused to the pre- and post-transplant structural proteins to assess changes in infectious particle production 23 (Fig

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