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[DOI] [PubMed] [Google Scholar] 26
Solutions kept at stable refrigerator temperatures generally outlast those exposed to temperature fluctuations or repeated handling, so consistent cold storage is the single biggest factor in maximizing usable shelf life
In the nuclear pathway, E2 binds either estrogen receptor (ER) or ER in the cytoplasm, forming heterodimers and homodimers that translocate to the nucleus, bind DNA at estrogen response elements (ERE), and activate the expression of ERE-dependent genes
Rare: may affect up to 1 in 1,000 people Acniform and bullous eruptions (acne-like and blistery skin eruptions) Not known: frequency cannot be estimated from the available data Headache, dizziness Nausea (feeling sick), vomiting, diarrhoea Malaise (feeling unwell) Rash, itching Injection site reactions including injection site pain, injection site erythema, injection site pruritus, injection site induration, and injection site swelling (Reactions at the site of the injection) Exanthema (a widespread skin rash) Chromaturia (unusual coloured urine) Fever Hot flushes (a feeling of intense heat with sweating and rapid heartbeat) Chills (feeling of coldness accompanied by shivering) Paraesthesia (feeling of pins and needles) Tremor (tremble or shakes) Hypokalaemia (decreased potassium levels in the blood) Reactive thrombocytosis (body produces too many platelets) Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse
Typical dietary intake ranges from 5-20 mg per day depending on mushroom consumption
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