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However, the significantly greater weight reduction associated with GLP-1 based therapies and their proven health benefits (e.g., reduction in cardiovascular disease with semaglutide [29] and improved sleep apnea with tirzepatide [30]), as well as a wider acceptance that medication is needed for sustained weight reduction success, has triggered a rapid surge in their uptake [31]
The study authors note that this effect size is similar to what is observed with many approved drug therapies, minus the side effects and costs
3 This relates to their core non-medication programme, not their GLP-1 offering, which launched later
The delivery timing should be meticulously determined based on a thorough maternal and fetal well-being evaluation
Patients with comorbid depression may benefit from bupropion's mood-increasing effects, though this shouldn't replace dedicated depression treatment
