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Frequencies observed in the present study were in accordance with reported allele frequencies in a Caucasian population and did not deviate from HardyWeinberg distribution

We have previously demonstrated that metabolic reprogramming is associated with a radioresistant phenotype in both in vitro and ex vivo models of oesophageal adenocarcinoma (21, 22) and rectal adenocarcinoma (23)

The most commonly reported side effects are gastrointestinal in nature , including nausea, vomiting, diarrhoea, constipation, and abdominal pain

crispatus) maintain optimal vaginal pH and produce antimicrobial compounds

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