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We find that, in contrast to previous studies, liver-specific GCLC expression in adult mice is not responsible for maintaining liver survival but instead sustains the expression of lipogenic enzymes and the abundance of triglycerides in the body

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Bile acid therapy for primary biliary cholangitis: Pathogenetic validation

Candidate pathways include anti-oxidant and DNA repair mechanisms which are modulated by individual genetic variation

Quantitative Real-Time Polymerase Chain Reaction (PCR) Quantitative real-time PCR reaction was performed using Rotor-Gene Q real time PCR cycler (Qiagen, Germany)