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39,40,446 Notably, GLP-1RAs exhibit pronounced efficacy in optimizing blood lipid profiles by effectively suppressing chylomicron secretion in the intestine, thereby mitigating the occurrence of postprandial hyperlipidemia

The most common side effects include nausea, vomiting, diarrhoea, decreased appetite, constipation, stomach pain, and indigestion, and these tend to be most noticeable during the initial weeks of treatment or shortly after a dose increase, typically easing as the body adjusts

Clinical research has evaluated doses up to 12 mg per week, depending on individual tolerance and treatment goals

Yes, but it would be an off-label use since Mounjaro is FDA-approved for type 2 diabetes, not obesity

In addition, GLP-1 secretion is positively correlated with postprandial bile acid concentration in healthy individuals [165]