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Moreover, significant progress has been made in biological therapies, particularly engineered cytokine modulators, macrophage-reprogramming strategies, and extracellular vesicle-based treatments derived from MSCs, all of which have demonstrated anti-inflammatory, chondroprotective, and immunomodulatory effects (Cotter et al., 2020

The risk of a poor injection technique is intravascular occlusion, which means it was injected into a blood vessel

While there is still much debate, there is agreement on many ARF management treatments and techniques, which opens the door to useful quality control and benchmarking (Ronco et al

Further investigation of the contents of these products is underway

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